Hi @jecho ,
Those EEVEE Settings depend on the size of your Volume (and when using Object Coordinates, possibly also on whether or not you have Applied the Scale of your Volume Object).
This might not be correct, but I think of it like this: if you cover 1 meter, taking 10 steps, the steps are smaller, than when you take 10 steps and cover 100 meter.
Same with the Resolution; a 1080 p resolution will be more than enough on a phone screen, but wiould look terrible in a cinema.
And to answer your question: no, it shouldn’t matter what GPU you use (at least not for the EEVEE Settings…it will impact the Render times and if it’s ‘really old’, Cycles might not be able to Render with it and has to revert to CPU).