That would be an interesting topic. I know Blender could definitely be used to create the visuals of a graphic novel. Although I’d probably approach it without going from the ground up. Modeling characters and props wouldn’t be much different than traditional modeling. Since these would be used as images you could probably also skip retopology unless needed. Rigging could also probably be skipped soon enough due to this: https://twitter.com/pablodp606/status/1160961114273910785
You could render each scene very quickly and even add in unique animated panels by rendering out a simple animation. You could create the inked look with a shader in Blender. Here is an example of a shader created in Blender that could work: https://cgcookie.com/lesson/clip-art
