@thecabbagedetective There’s no such thing as stupid question 🙂
As usual, the answer would be it depends 🙂 It depends on the size of the lumps and the size of the quad you will retopo over. Usually, since retopo involves larger quad scale, the lumpiness vanishes and you get a smoother result.
If you use a subsurf and a shrinkwrap (over the sculpt) on your retopologized model then the lumps will reappear. @theluthier explains it well here. Mind thatt it’s not a car but a buff male body and the purpose is to recover the details but you get the idea 😀
https://www.youtube.com/watch?v=MU7EQjauKNo