@dostovel You can of course leave everything at it’s default, but remember that the developers also left open a lot of customizability of Blender; they never said that the defaults are the best…
As long as you’re not making tutorials, I think you should feel free to make Blender the way it works best for you.
That being said, I do think, that it’s good to try the defaults for some time and then, when you can’t get used to some things, you can always change them. That is what I did with the ‘old’ Blender as well..,.