Hi Muhammed @haamza ,
I think, that in this case, you can just leave it like that; it will not be noticeable, when this is textured.
You can also try to move some Vertices around, trying to get the spacing more even (the area above the hole is more dense, than the side, for instance), Some of the Quads above the hole seem to be non-flat, that might be causing the shading issue. But the result will not be using the Normals of the retopologized Mesh, but those of the High Poly Mesh, so that shouldn’t be a problem.
Or, if you want, you can re-do the area around the holes (left and right from the hole are different), that’s up to you.
If you are going to apply for a job in the industry, you don’t want to showcase it like this, but otherwise you’ll be fine to leave it (in my opinion).