Hi @rubybard ,
I have noticed that as well; saving appears to make things worse.
Try to save less; only when finished fixing all the Verts in all Multires levels (from the lowest to the highest level)…
You might also try this (haven’t tested it yet, nut it might work): if you can, Mask out the head (without the exploded Vertices) and then use the Mesh Filter, set to Smooth…
