Aside from adjusting to the visual appearance of the 2.8 user interface, I would say you shouldn’t have too much trouble following along one of the sculpting courses using 2.8. When Kent Trammel did a live class a few months ago which did some sculpting in 2.8, there were some frustrating issues with some of the keyboard shortcuts for the different sculpting brush types; but those problems have been resolved now – assuming you’ve got the newest edition of 2.8 that is. In fact I think all or most of the brushes still have the same shortcuts you’ll learn for them in the 2.79 course videos. If in doubt, just hit Spacebar while in sculpt mode and it brings up a list of brushes right at your cursor location – you can select them there, but the list also shows all the shortcuts for all the brushes.
As a suggestion: you CAN still actually change your normal default 3D viewport to Sculpt Mode as needed; but I personally find it more useful to just click on the Sculpting tab at the top of the window to go to the Sculpting workspace, which is already in Sculpt Mode and all set up. I find switching between the different workspace tabs makes it a lot easier to go back and forth between different kinds of work without having to fiddle with the individual interface elements too much – but if you would rather keep your UI looking more like the one in the video to reduce confusion, you can certainly do that of course.