Hello raijkeraijke, I can explain the strange distortions you get; these are caused, because for some reason, your curve (‘tyre’) itself is distorted (select the curve and go into edit mode and you can see that). So there”s an easy solution: delete your curve and add a new one. Update it in your modifiers of your ‘Cylinder’ and it works as expected, at least without the crazy distortions…
But it probably doesn’t give you the desired result. If you can get it to work, then I would be happy if you could share, how you did that!
I couldn’t and used another method for the tire; there is a tutorial by Chris Plush on modeling a car tire and he uses a simple deform modifier to bend it around. https://www.youtube.com/watch?v=PcIu2hIO4Og