Hi James,
That is indeed a fantastic look!
But I don’t know of any ‘shortcuts’ to make something like that. Coincidentally, I have been playing with simple origami paper models:

and this was already a huge challenge…and it doesn’t even have the paper wrinkles and so (I tried, but couldn’t get anywhere near a realistic look).
I am sure, that it is possible and it will be worth the trouble, but you’re probably in for a bumpy ride. That said, please go ahead and figure this out!
Maybe you can use some shrinkwrapping using low poly Meshes, to get an initial, crude look of a head (or other model) wrapped in paper. Then use Sculpting to refine the shapes and add the wrinkle detail…