Hi @gailgongster ,
As far as I know, if you draw (D) on a Frame, that drawing (Annotation) stays if you go further along the Timeline, until you make a new Annotation.
So, make an Annotation on Frame 7, then make a new Annotation on Frame 23…The first drawing will be visible from Frame 7 till 22 and then switch to the second drawing on Frame 23…
If you Lock the Annotation Layer, then you can draw anywhere along the Timeline and it will always be visible; draw on frame 17, Lock it and the draw something on frame 43 and go to any Frame and both drawings will be there.