Hello!
If you could give us more information on your workflow it might help us give better advice. For instance, are you working on an object using dyntopo or remesh? Or a retopologized object with multi-resolution?
I can say that ZBrush has a method of being able to handle very high resolution sculpting without much slowing that is almost magical. Blender isn’t at that level…yet….but a full redesign is in the works: https://twitter.com/pablodp606/status/1309556563787550720